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nocebo effect
noun
: the development of adverse side effects or worsening in the condition of a patient that occurs in response to medical treatment but cannot be considered due to the specific treatment used
With a nocebo effect, if test subjects believe there may be side effects, they often experience them. Again, expectations shape reality.—
Sanjay Gupta
Examples of nocebo effect in a Sentence
Recent Examples on the Web
The data clearly indicated that a nocebo effect was occurring – in other words, participants were experiencing an entirely psychological phenomenon in which a harmless substance causes a harmful effect.
—
Elsbeth Sites, Discover Magazine, 3 June 2014
The relevance of the nocebo effect is not limited to clinical trials.
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Guest Blogger, Discover Magazine, 24 July 2012
Or a nocebo effect when expectations make people feel worse rather than better.
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Neuroskeptic, Discover Magazine, 8 Sep. 2010
The placebo effect also has a shadowy twin: the nocebo effect.
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Carl Engelking, Discover Magazine, 5 Oct. 2017
The nocebo effect is another important aspect of mindset.
—
Jennifer C. Lovejoy, Scientific American, 7 Dec. 2022
Marino, who watched the video, told the San Diego Union-Tribune a nocebo effect could explain Faiivae's reaction since his symptoms did not suggest an overdose.
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Miriam Fauzia, USA TODAY, 25 Aug. 2021
The psychology of myalgias involves the nocebo effect, the flip side of the placebo effect.
—
Richard Klasco, New York Times, 1 June 2018
The researchers also pinpointed areas of the brain that seemed to be involved in the nocebo effect overall.
—
Beth Mole, Ars Technica, 9 Oct. 2017
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Word History
First Known Use
1969, in the meaning defined above
Dictionary Entries Near nocebo effect
Cite this Entry
“Nocebo effect.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/nocebo%20effect. Accessed 19 Feb. 2025.
Medical Definition
nocebo effect
noun
: the development of adverse side effects or worsening in the condition of a patient that occurs in response to medical treatment but cannot be considered due to the specific treatment used
With a nocebo effect, if test subjects believe there may be side effects, they often experience them. Again, expectations shape reality.—
Sanjay Gupta, Chasing Life: New Discoveries In The Search For Immortality …
The placebo effect has an evil twin: the nocebo effect, in which dummy pills and negative expectations can produce harmful effects.—
Helen Pilcher, New Scientist
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